
Airway pressure amplitude is significantly attenuated throughout the respiratory system and mechanical strain and stress on the alveoli are theoretically minimized. Carbon dioxide (CO 2) is cleared based on the power (amplitude) setting and frequency, with lower frequencies resulting in higher V T and CO 2 clearance.

During HFOV, mean airway pressure is set and gas is then displaced towards and away from the patient through a piston. High-frequency oscillatory ventilation (HFOV) is a type of invasive mechanical ventilation that employs supra-physiologic respiratory rates and low tidal volumes (V T) that approximate the anatomic deadspace. 5Duke-NUS Medical School, Singapore, Singapore.4Duke University Medical Center, Division of Pediatric Critical Care Medicine, Durham, NC, United States.3University of California, Davis, Respiratory Care Services, Sacramento, CA, United States.


1Duke University Medical Center, Respiratory Care Services, Durham, NC, United States.
